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α- and β-Substituted phosphonate analogs of LPA as autotaxin inhibitors
Autotaxin (ATX) is an attractive pharmacological target due to its lysophospholipase D activity which leads to the production of lysophosphatidic acid (LPA). Blockage of ATX produced LPA by small molecules could be a potential anticancer chemotherapy. In our previous study, we have identified the tw...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2007
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2907913/ https://ncbi.nlm.nih.gov/pubmed/18082408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.11.078 |
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