α-Substituted Phosphonate Analogues of Lysophosphatidic Acid (LPA) Selectively Inhibit Production and Action of LPA

Isoform-selective agonists and antagonists of the lysophosphatidic acid (LPA) G-protein-coupled receptors (GPCRs) have important potential applications in cell biology and therapy. LPA GPCRs regulate cancer cell proliferation, invasion, angiogenesis, and biochemical resistance to chemotherapy- and r...

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Huvudupphovsmän: Jiang, Guowei, Xu, Yong, Fujiwara, Yuko, Tsukahara, Tamotsu, Tsukahara, Ryoko, Gajewiak, Joanna, Tigyi, Gabor, Prestwich, Glenn D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505595/
https://ncbi.nlm.nih.gov/pubmed/17443831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.200600280
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