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Synthesis, Pharmacology, and Cell Biology of sn-2-Aminooxy Analogues of Lysophosphatidic Acid
[Image: see text] An efficient enantioselective synthesis of sn-2-aminooxy (AO) analogues of lysophosphatidic acid (LPA) that possess palmitoyl and oleoyl acyl chains is presented. Both sn-2-AO LPA analogues are agonists for the LPA(1), LPA(2), and LPA(4) G-protein-coupled receptors, but antagonists...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3510981/ https://ncbi.nlm.nih.gov/pubmed/18284246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol7030747 |
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