Lysophosphatidic Acid-induced Arterial Wall Remodeling: Requirement of PPAR γ but Not LPA(1) or LPA(2) GPCR

Lysophosphatidic acid (LPA) and its ether analog alkyl-glycerophosphate (AGP) elicit arterial wall remodeling when applied intralumenally into the uninjured carotid artery. LPA is the ligand of eight GPCRs and the peroxisome proliferator-activated receptor γ (PPARγ). We pursued a gene knockout strat...

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Hlavní autoři: Cheng, Yunhui, Makarova, Natalia, Tsukahara, Ryoko, Guo, Huazhang, E, Shuyu, Farrar, Patricia, Balazs, Louisa, Zhang, Chunxiang, Tigyi, Gabor
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760670/
https://ncbi.nlm.nih.gov/pubmed/19709640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2009.08.003
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