लोड हो रहा है...

Benzothiophene Carboxylate Derivatives as Novel Allosteric Inhibitors of Branched-chain α-Ketoacid Dehydrogenase Kinase

The mitochondrial branched-chain α-ketoacid dehydrogenase complex (BCKDC) is negatively regulated by reversible phosphorylation. BCKDC kinase (BDK) inhibitors that augment BCKDC flux have been shown to reduce branched-chain amino acid (BCAA) concentrations in vivo. In the present study, we employed...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Tso, Shih-Chia, Gui, Wen-Jun, Wu, Cheng-Yang, Chuang, Jacinta L., Qi, Xiangbing, Skvorak, Kristen J., Dorko, Kenneth, Wallace, Amy L., Morlock, Lorraine K., Lee, Brendan H., Hutson, Susan M., Strom, Stephen C., Williams, Noelle S., Tambar, Uttam K., Wynn, R. Max, Chuang, David T.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110271/
https://ncbi.nlm.nih.gov/pubmed/24895126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.569251
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!