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Microsatellite Interruptions Stabilize Primate Genomes and Exist as Population-Specific Single Nucleotide Polymorphisms within Individual Human Genomes

Interruptions of microsatellite sequences impact genome evolution and can alter disease manifestation. However, human polymorphism levels at interrupted microsatellites (iMSs) are not known at a genome-wide scale, and the pathways for gaining interruptions are poorly understood. Using the 1000 Genom...

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Autors principals: Ananda, Guruprasad, Hile, Suzanne E., Breski, Amanda, Wang, Yanli, Kelkar, Yogeshwar, Makova, Kateryna D., Eckert, Kristin A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102424/
https://ncbi.nlm.nih.gov/pubmed/25033203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004498
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