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Every Microsatellite is Different: Intrinsic DNA Features Dictate Mutagenesis of Common Microsatellites Present in the Human Genome

Microsatellite sequences are ubiquitous in the human genome and are important regulators of genome function. Here, we examine the mutational mechanisms governing the stability of highly abundant mono-, di-, and tetranucleotide microsatellites. Microsatellite mutation rate estimates from pedigree ana...

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Autori principali: Eckert, Kristin A., Hile, Suzanne E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731485/
https://ncbi.nlm.nih.gov/pubmed/19306292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.20499
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