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The In Vitro Fidelity Of Yeast DNA Polymerase δ And Polymerase ε Holoenzymes During Dinucleotide Microsatellite DNA Synthesis

Elucidating the sources of genetic variation within microsatellite alleles has important implications for understanding the etiology of human diseases. Mismatch repair is a well described pathway for the suppression of microsatellite instability. However, the cellular polymerases responsible for gen...

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Detalhes bibliográficos
Main Authors: Abdulovic, Amy L., Hile, Suzanne E., Kunkel, Thomas A., Eckert, Kristin A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121764/
https://ncbi.nlm.nih.gov/pubmed/21429821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2011.02.003
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