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Yeast DNA Polymerase ϵ Catalytic Core and Holoenzyme Have Comparable Catalytic Rates
The holoenzyme of yeast DNA polymerase ϵ (Pol ϵ) consists of four subunits: Pol2, Dpb2, Dpb3, and Dpb4. A protease-sensitive site results in an N-terminal proteolytic fragment of Pol2, called Pol2(core), that consists of the catalytic core of Pol ϵ and retains both polymerase and exonuclease activit...
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| Veröffentlicht in: | J Biol Chem |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4319046/ https://ncbi.nlm.nih.gov/pubmed/25538242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.615278 |
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