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Translesion Synthesis of Abasic Sites by Yeast DNA Polymerase ϵ
Studies of replicative DNA polymerases have led to the generalization that abasic sites are strong blocks to DNA replication. Here we show that yeast replicative DNA polymerase ϵ bypasses a model abasic site with comparable efficiency to Pol η and Dpo4, two translesion polymerases. DNA polymerase ϵ...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2797225/ https://ncbi.nlm.nih.gov/pubmed/19776424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.043927 |
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