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In Vitro Gap-directed Translesion DNA Synthesis of an Abasic Site Involving Human DNA Polymerases ϵ, λ, and β
DNA polymerase (pol) ϵ is thought to be the leading strand replicase in eukaryotes, whereas pols λ and β are believed to be mainly involved in re-synthesis steps of DNA repair. DNA elongation by the human pol ϵ is halted by an abasic site (apurinic/apyrimidinic (AP) site). In this study, we present...
में बचाया:
मुख्य लेखकों: | , , , , , , , , , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
American Society for Biochemistry and Molecular Biology
2011
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3173188/ https://ncbi.nlm.nih.gov/pubmed/21757740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.246611 |
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