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Comparison of the kinetic parameters of the truncated catalytic subunit and holoenzyme of human DNA polymerase ε

Numerous genetic studies have provided compelling evidence to establish DNA polymerase ε (Polε) as the primary DNA polymerase responsible for leading strand synthesis during eukaryotic nuclear genome replication. Polε is a heterotetramer consisting of a large catalytic subunit that contains the cons...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Zahurancik, Walter J., Baranovskiy, Andrey G., Tahirov, Tahir H., Suo, Zucai
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426069/
https://ncbi.nlm.nih.gov/pubmed/25684708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2015.01.008
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