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Comparison of the kinetic parameters of the truncated catalytic subunit and holoenzyme of human DNA polymerase ε
Numerous genetic studies have provided compelling evidence to establish DNA polymerase ε (Polε) as the primary DNA polymerase responsible for leading strand synthesis during eukaryotic nuclear genome replication. Polε is a heterotetramer consisting of a large catalytic subunit that contains the cons...
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| Udgivet i: | DNA Repair (Amst) |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4426069/ https://ncbi.nlm.nih.gov/pubmed/25684708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2015.01.008 |
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