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DNA polymerase kappa produces interrupted mutations and displays polar pausing within mononucleotide microsatellite sequences

Microsatellites are ubiquitously present in eukaryotic genomes and are implicated as positive factors in evolution. At the nucleotide level, microsatellites undergo slippage events that alter allele length and base changes that interrupt the repetitive tract. We examined DNA polymerase errors within...

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Detalhes bibliográficos
Main Authors: Hile, Suzanne E., Eckert, Kristin A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2241860/
https://ncbi.nlm.nih.gov/pubmed/18079151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm1089
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