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RNA polymerase-induced remodelling of NusA produces a pause enhancement complex

Pausing during transcription elongation is a fundamental activity in all kingdoms of life. In bacteria, the essential protein NusA modulates transcriptional pausing, but its mechanism of action has remained enigmatic. By combining structural and functional studies we show that a helical rearrangemen...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Ma, Cong, Mobli, Mehdi, Yang, Xiao, Keller, Andrew N., King, Glenn F., Lewis, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357713/
https://ncbi.nlm.nih.gov/pubmed/25690895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv108
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