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RNA polymerase-induced remodelling of NusA produces a pause enhancement complex
Pausing during transcription elongation is a fundamental activity in all kingdoms of life. In bacteria, the essential protein NusA modulates transcriptional pausing, but its mechanism of action has remained enigmatic. By combining structural and functional studies we show that a helical rearrangemen...
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Publicado no: | Nucleic Acids Res |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4357713/ https://ncbi.nlm.nih.gov/pubmed/25690895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv108 |
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