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A matter of life or death: How microsatellites emerge in and vanish from the human genome

Microsatellites—tandem repeats of short DNA motifs—are abundant in the human genome and have high mutation rates. While microsatellite instability is implicated in numerous genetic diseases, the molecular processes involved in their emergence and disappearance are still not well understood. Microsat...

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Detalhes bibliográficos
Main Authors: Kelkar, Yogeshwar D., Eckert, Kristin A., Chiaromonte, Francesca, Makova, Kateryna D.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227094/
https://ncbi.nlm.nih.gov/pubmed/21994250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.122937.111
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