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What Is a Microsatellite: A Computational and Experimental Definition Based upon Repeat Mutational Behavior at A/T and GT/AC Repeats

Microsatellites are abundant in eukaryotic genomes and have high rates of strand slippage-induced repeat number alterations. They are popular genetic markers, and their mutations are associated with numerous neurological diseases. However, the minimal number of repeats required to constitute a micro...

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Библиографические подробности
Главные авторы: Kelkar, Yogeshwar D., Strubczewski, Noelle, Hile, Suzanne E., Chiaromonte, Francesca, Eckert, Kristin A., Makova, Kateryna D.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940325/
https://ncbi.nlm.nih.gov/pubmed/20668018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evq046
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