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The genome-wide determinants of human and chimpanzee microsatellite evolution

Mutation rates of microsatellites vary greatly among loci. The causes of this heterogeneity remain largely enigmatic yet are crucial for understanding numerous human neurological diseases and genetic instability in cancer. In this first genome-wide study, the relative contributions of intrinsic feat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kelkar, Yogeshwar D., Tyekucheva, Svitlana, Chiaromonte, Francesca, Makova, Kateryna D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2134767/
https://ncbi.nlm.nih.gov/pubmed/18032720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.7113408
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