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Regulation of mTORC1 by amino acids
The mechanistic target of rapamycin complex I (mTORC1) is a central regulator of cellular and organismal growth and hyperactivation of this pathway is implicated in the pathogenesis of many human diseases, including cancer and diabetes. mTORC1 promotes growth in response to the availability of nutri...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4074565/ https://ncbi.nlm.nih.gov/pubmed/24698685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2014.03.003 |
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