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Rag Proteins Regulate Amino Acid-Induced mTORC1 Signaling

The serum and nutrient-sensitive protein kinase mTOR is a master regulator of cell growth and survival. The mechanisms through which nutrients regulate mTOR have been one of the major unanswered questions in the mTOR field. Identification of rag family of GTPases as mediators of amino acid signaling...

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Detalhes bibliográficos
Main Authors: Sancak, Yasemin, Sabatini, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390249/
https://ncbi.nlm.nih.gov/pubmed/19143648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST0370289
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