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Regulation of mTORC1 by amino acids

The mechanistic target of rapamycin complex I (mTORC1) is a central regulator of cellular and organismal growth and hyperactivation of this pathway is implicated in the pathogenesis of many human diseases, including cancer and diabetes. mTORC1 promotes growth in response to the availability of nutri...

詳細記述

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書誌詳細
主要な著者: Bar-Peled, Liron, Sabatini, David M.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074565/
https://ncbi.nlm.nih.gov/pubmed/24698685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2014.03.003
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