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Regulation of mTORC1 by amino acids

The mechanistic target of rapamycin complex I (mTORC1) is a central regulator of cellular and organismal growth and hyperactivation of this pathway is implicated in the pathogenesis of many human diseases, including cancer and diabetes. mTORC1 promotes growth in response to the availability of nutri...

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Bibliografski detalji
Glavni autori: Bar-Peled, Liron, Sabatini, David M.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074565/
https://ncbi.nlm.nih.gov/pubmed/24698685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2014.03.003
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