ATRA-Induced Cellular Differentiation and CD38 Expression Inhibits Acquisition of BCR-ABL Mutations for CML Acquired Resistance

Acquired resistance through genetic mutations is a major obstacle in targeted cancer therapy, but the underlying mechanisms are poorly understood. Here we studied mechanisms of acquired resistance of chronic myeloid leukemia (CML) to tyrosine kinase inhibitors (TKIs) by examining genome-wide gene ex...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wang, Zhiqiang, Liu, Zheng, Wu, Xiwei, Chu, Su, Wang, Jinhui, Yuan, Hongfeng, Roth, Mendel, Yuan, Yate-Ching, Bhatia, Ravi, Chen, WenYong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2014
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072521/
https://ncbi.nlm.nih.gov/pubmed/24967705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004414
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