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TET1 is a maintenance DNA demethylase that prevents methylation spreading in differentiated cells

TET1 is a 5-methylcytosine dioxygenase and its DNA demethylating activity has been implicated in pluripotency and reprogramming. However, the precise role of TET1 in DNA methylation regulation outside of developmental reprogramming is still unclear. Here, we show that overexpression of the TET1 cata...

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Detalhes bibliográficos
Main Authors: Jin, Chunlei, Lu, Yue, Jelinek, Jaroslav, Liang, Shoudan, Estecio, Marcos R.H., Barton, Michelle Craig, Issa, Jean-Pierre J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066785/
https://ncbi.nlm.nih.gov/pubmed/24875481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku372
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