Conserved DNA methylation patterns in healthy blood cells and extensive changes in leukemia measured by a new quantitative technique

Genome wide analysis of DNA methylation provides important information in a variety of diseases, including cancer. Here, we describe a simple method, Digital Restriction Enzyme Analysis of Methylation (DREAM), based on next generation sequencing analysis of methylation-specific signatures created by...

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Detalhes bibliográficos
Main Authors: Jelinek, Jaroslav, Liang, Shoudan, Lu, Yue, He, Rong, Ramagli, Louis S., Shpall, Elizabeth J., Estecio, Marcos R.H., Issa, Jean-Pierre J.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528692/
https://ncbi.nlm.nih.gov/pubmed/23075513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.22552
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