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TET1 is a maintenance DNA demethylase that prevents methylation spreading in differentiated cells
TET1 is a 5-methylcytosine dioxygenase and its DNA demethylating activity has been implicated in pluripotency and reprogramming. However, the precise role of TET1 in DNA methylation regulation outside of developmental reprogramming is still unclear. Here, we show that overexpression of the TET1 cata...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4066785/ https://ncbi.nlm.nih.gov/pubmed/24875481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku372 |
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