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TET1 is a maintenance DNA demethylase that prevents methylation spreading in differentiated cells

TET1 is a 5-methylcytosine dioxygenase and its DNA demethylating activity has been implicated in pluripotency and reprogramming. However, the precise role of TET1 in DNA methylation regulation outside of developmental reprogramming is still unclear. Here, we show that overexpression of the TET1 cata...

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Bibliografski detalji
Glavni autori: Jin, Chunlei, Lu, Yue, Jelinek, Jaroslav, Liang, Shoudan, Estecio, Marcos R.H., Barton, Michelle Craig, Issa, Jean-Pierre J.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066785/
https://ncbi.nlm.nih.gov/pubmed/24875481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku372
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