Načítá se...

Wild-type H- and N-Ras promote mutant K-Ras driven tumorigenesis by modulating the DNA damage response

Mutations in KRAS are prevalent in human cancers and universally predictive of resistance to anti-cancer therapeutics. Although it is widely accepted that acquisition of an activating mutation endows RAS genes with functional autonomy, recent studies suggest that the wild-type forms of Ras may contr...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Grabocka, Elda, Pylayeva-Gupta, Yuliya, Jones, Mathew JK, Lubkov, Veronica, Yemanaberhan, Eyoel, Taylor, Laura, Jeng, Hao Hsuan, Bar-Sagi, Dafna
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063560/
https://ncbi.nlm.nih.gov/pubmed/24525237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2014.01.005
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!