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Mutant KRAS enhances tumor cell fitness by upregulating stress granules
There is growing evidence that stress-coping mechanisms represent tumor cell vulnerabilities that may function as therapeutically beneficial targets. Recent work has delineated an integrated stress adaptation mechanism that is characterized by the formation of cytoplasmic mRNA/protein foci termed st...
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| 出版年: | Cell |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5441683/ https://ncbi.nlm.nih.gov/pubmed/27984728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.11.035 |
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