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Mutant KRAS enhances tumor cell fitness by upregulating stress granules
There is growing evidence that stress-coping mechanisms represent tumor cell vulnerabilities that may function as therapeutically beneficial targets. Recent work has delineated an integrated stress adaptation mechanism that is characterized by the formation of cytoplasmic mRNA/protein foci termed st...
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| Publicado en: | Cell |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5441683/ https://ncbi.nlm.nih.gov/pubmed/27984728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.11.035 |
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