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Molecular Pathways: Targeting the Dependence of Mutant RAS Cancers on the DNA Damage Response

Of the genes mutated in cancer, RAS remains the most elusive to target. Recent technological advances and discoveries have greatly expanded our knowledge of the biology of oncogenic Ras and its role in cancer. As such, it has become apparent that a property that intimately accompanies RAS-driven tum...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Grabocka, Elda, Commisso, Cosimo, Bar-Sagi, Dafna
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359952/
https://ncbi.nlm.nih.gov/pubmed/25424849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-0650
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