The pervasiveness of macropinocytosis in oncological malignancies

по Commisso, Cosimo
Опубликовано в: Philos Trans R Soc Lond B Biol Sci (2019)

Macropinocytosis in Cancer: A Complex Signaling Network

по Zhang, Yijuan, Commisso, Cosimo
Опубликовано в: Trends Cancer (2019)

The NHR1 Domain of Neuralized Binds Delta and Mediates Delta Trafficking and Notch Signaling

по Commisso, Cosimo, Boulianne, Gabrielle L.
Опубликовано 2007

Macropinocytosis: A Metabolic Adaptation to Nutrient Stress in Cancer

по Recouvreux, Maria Victoria, Commisso, Cosimo
Опубликовано в: Front Endocrinol (Lausanne) (2017)

Rac1 and EGFR cooperate to activate Pak in response to nutrient stress

по Lee, Szu-Wei, Commisso, Cosimo
Опубликовано в: Biochem Biophys Res Commun (2020)

Metabolic regulation of EGFR effector and feedback signaling in pancreatic cancer cells requires K-Ras

по Lee, Szu-Wei, Commisso, Cosimo
Опубликовано в: Biochem Biophys Res Commun (2020)

The Golgi as a “Proton Sink” in Cancer

по Galenkamp, Koen M. O., Commisso, Cosimo
Опубликовано в: Front Cell Dev Biol (2021)

Molecular Pathways: Targeting the Dependence of Mutant RAS Cancers on the DNA Damage Response

по Grabocka, Elda, Commisso, Cosimo, Bar-Sagi, Dafna
Опубликовано в: Clin Cancer Res (2014)

Determining the macropinocytic index of cancer cells through a quantitative image-based assay

по Commisso, Cosimo, Flinn, Rory J., Bar-Sagi, Dafna
Опубликовано 2014

High-Content, Full Genome siRNA Screen for Regulators of Oncogenic HRAS-Driven Macropinocytosis

по Fennell, Myles, Commisso, Cosimo, Ramirez, Craig, Garippa, Ralph, Bar-Sagi, Dafna
Опубликовано в: Assay Drug Dev Technol (2015)

Components of the ESCRT Pathway, DFG16, and YGR122w Are Required for Rim101 To Act as a Corepressor with Nrg1 at the Negative Regulatory Element of the DIT1 Gene of Saccharomyces c...

по Rothfels, Karen, Tanny, Jason C., Molnar, Enikö, Friesen, Helena, Commisso, Cosimo, Segall, Jacqueline
Опубликовано 2005

EGFR/Pak Signaling Selectively Regulates Glutamine Deprivation-Induced Macropinocytosis

по Lee, Szu-Wei, Zhang, Yijuan, Jung, Michael, Cruz, Nathalia, Alas, Basheer, Commisso, Cosimo
Опубликовано в: Dev Cell (2019)

Functional Analysis of the NHR2 Domain Indicates that Oligomerization of Neuralized Regulates Ubiquitination and Endocytosis of Delta during Notch Signaling

по Liu, Sili, Bonner, Julia Maeve, Chanet, Soline, Commisso, Cosimo, Skwarek, Lara C., Schweisguth, François, Boulianne, Gabrielle L.
Опубликовано 2012

Glutamine depletion regulates Slug to promote EMT and metastasis in pancreatic cancer

по Recouvreux, Maria Victoria, Moldenhauer, Matthew R., Galenkamp, Koen M.O., Jung, Michael, James, Brian, Zhang, Yijuan, Lowy, Andrew, Bagchi, Anindya, Commisso, Cosimo
Опубликовано в: J Exp Med (2020)

Golgi Acidification by NHE7 Regulates Cytosolic pH Homeostasis in Pancreatic Cancer Cells

по Galenkamp, Koen M.O., Sosicka, Paulina, Jung, Michael, Recouvreux, M. Victoria, Zhang, Yijuan, Moldenhauer, Matthew R., Brandi, Giovanni, Freeze, Hudson H., Commisso, Cosimo
Опубликовано в: Cancer Discov (2020)

Macropinocytosis in Cancer-Associated Fibroblasts is Dependent on CaMKK2/ARHGEF2 Signaling and Functions to Support Tumor and Stromal Cell Fitness

по Zhang, Yijuan, Recouvreux, M. Victoria, Jung, Michael, Galenkamp, Koen M.O., Li, Yunbo, Zagnitko, Olga, Scott, David A., Lowy, Andrew M., Commisso, Cosimo
Опубликовано в: Cancer Discov (2021)

Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein

по Kamphorst, Jurre J., Nofal, Michel, Commisso, Cosimo, Hackett, Sean R., Lu, Wenyun, Grabocka, Elda, Vander Heiden, Matthew G., Miller, George, Drebin, Jeffrey A., Bar-Sagi, Dafna, Thompson, Craig B., Rabinowitz, Joshua D.
Опубликовано в: Cancer Res (2015)

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells

по Commisso, Cosimo, Davidson, Shawn M., Soydaner-Azeloglu, Rengin G., Parker, Seth J., Kamphorst, Jurre J., Hackett, Sean, Grabocka, Elda, Nofal, Michel, Drebin, Jeffrey A., Thompson, Craig B., Rabinowitz, Joshua D., Metallo, Christian M., Heiden, Matthew G. Vander, Bar-Sagi, Dafna
Опубликовано 2013

Loss of HIF1A From Pancreatic Cancer Cells Increases Expression of PPP1R1B and Degradation of p53 to Promote Invasion and Metastasis

по Tiwari, Ashutosh, Tashiro, Kojiro, Dixit, Ajay, Soni, Aditi, Vogel, Keianna, Hall, Bryan, Shafqat, Iram, Slaughter, Joseph, Param, Nesteen, Le, An, Saunders, Emily, Paithane, Utkarsha, Garcia, Guillermina, Campos, Alexandre Rosa, Zettervall, Jon, Carlson, Marjorie, Starr, Timothy K., Marahrens, York, Deshpande, Aniruddha J., Commisso, Cosimo, Provenzano, Paolo P, Bagchi, Anindya
Опубликовано в: Gastroenterology (2020)