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EGFR/Pak Signaling Selectively Regulates Glutamine Deprivation-Induced Macropinocytosis

Macropinocytosis has emerged as an important nutrient scavenging pathway that supports tumor cell fitness. By internalizing extracellular protein and targeting it for lysosomal degradation, this endocytic pathway functions as an amino acid supply route, permitting tumor cell growth and survival desp...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Lee, Szu-Wei, Zhang, Yijuan, Jung, Michael, Cruz, Nathalia, Alas, Basheer, Commisso, Cosimo
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684838/
https://ncbi.nlm.nih.gov/pubmed/31257175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.05.043
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