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The pervasiveness of macropinocytosis in oncological malignancies

In tumour cells, macropinocytosis functions as an amino acid supply route and supports cancer cell survival and proliferation. Initially demonstrated in oncogenic KRAS-driven models of pancreatic cancer, macropinocytosis triggers the internalization of extracellular proteins via discrete endocytic v...

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Bibliografiske detaljer
Udgivet i:Philos Trans R Soc Lond B Biol Sci
Hovedforfatter: Commisso, Cosimo
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6304744/
https://ncbi.nlm.nih.gov/pubmed/30967003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2018.0153
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