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The pervasiveness of macropinocytosis in oncological malignancies
In tumour cells, macropinocytosis functions as an amino acid supply route and supports cancer cell survival and proliferation. Initially demonstrated in oncogenic KRAS-driven models of pancreatic cancer, macropinocytosis triggers the internalization of extracellular proteins via discrete endocytic v...
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| Publicado no: | Philos Trans R Soc Lond B Biol Sci |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6304744/ https://ncbi.nlm.nih.gov/pubmed/30967003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2018.0153 |
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