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High-Content, Full Genome siRNA Screen for Regulators of Oncogenic HRAS-Driven Macropinocytosis

Uptake of nutrients, such as glucose and amino acids, is critical to support cell growth and is typically mediated by cell surface transporters. An alternative mechanism for the bulk uptake of nutrients from the extracellular space is macropinocytosis, a nonclathrin, and nonreceptor-mediated endocyt...

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Detalhes bibliográficos
Publicado no:Assay Drug Dev Technol
Main Authors: Fennell, Myles, Commisso, Cosimo, Ramirez, Craig, Garippa, Ralph, Bar-Sagi, Dafna
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554932/
https://ncbi.nlm.nih.gov/pubmed/26267765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2015.660
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