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High-Content, Full Genome siRNA Screen for Regulators of Oncogenic HRAS-Driven Macropinocytosis

Uptake of nutrients, such as glucose and amino acids, is critical to support cell growth and is typically mediated by cell surface transporters. An alternative mechanism for the bulk uptake of nutrients from the extracellular space is macropinocytosis, a nonclathrin, and nonreceptor-mediated endocyt...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Assay Drug Dev Technol
मुख्य लेखकों: Fennell, Myles, Commisso, Cosimo, Ramirez, Craig, Garippa, Ralph, Bar-Sagi, Dafna
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Mary Ann Liebert, Inc. 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554932/
https://ncbi.nlm.nih.gov/pubmed/26267765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2015.660
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