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High-Content, Full Genome siRNA Screen for Regulators of Oncogenic HRAS-Driven Macropinocytosis

Uptake of nutrients, such as glucose and amino acids, is critical to support cell growth and is typically mediated by cell surface transporters. An alternative mechanism for the bulk uptake of nutrients from the extracellular space is macropinocytosis, a nonclathrin, and nonreceptor-mediated endocyt...

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Опубликовано в: :Assay Drug Dev Technol
Главные авторы: Fennell, Myles, Commisso, Cosimo, Ramirez, Craig, Garippa, Ralph, Bar-Sagi, Dafna
Формат: Artigo
Язык:Inglês
Опубликовано: Mary Ann Liebert, Inc. 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554932/
https://ncbi.nlm.nih.gov/pubmed/26267765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2015.660
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