High-Content, Full Genome siRNA Screen for Regulators of Oncogenic HRAS-Driven Macropinocytosis

Uptake of nutrients, such as glucose and amino acids, is critical to support cell growth and is typically mediated by cell surface transporters. An alternative mechanism for the bulk uptake of nutrients from the extracellular space is macropinocytosis, a nonclathrin, and nonreceptor-mediated endocyt...

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Bibliographic Details
Published in:Assay Drug Dev Technol
Main Authors: Fennell, Myles, Commisso, Cosimo, Ramirez, Craig, Garippa, Ralph, Bar-Sagi, Dafna
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2015
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554932/
https://ncbi.nlm.nih.gov/pubmed/26267765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2015.660
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