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The NHR1 Domain of Neuralized Binds Delta and Mediates Delta Trafficking and Notch Signaling
Notch signaling, which is crucial to metazoan development, requires endocytosis of Notch ligands, such as Delta and Serrate. Neuralized is a plasma membrane-associated ubiquitin ligase that is required for neural development and Delta internalization. Neuralized is comprised of three domains that in...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The American Society for Cell Biology
2007
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1751308/ https://ncbi.nlm.nih.gov/pubmed/17065551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-08-0753 |
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