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RAS oncogenes: weaving a tumorigenic web

RAS proteins are essential components of signalling pathways that emanate from cell surface receptors. Oncogenic activation of these proteins owing to missense mutations is frequently detected in several types of cancer. A wealth of biochemical and genetic studies indicates that RAS proteins control...

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Detalhes bibliográficos
Main Authors: Pylayeva-Gupta, Yuliya, Grabocka, Elda, Bar-Sagi, Dafna
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632399/
https://ncbi.nlm.nih.gov/pubmed/21993244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3106
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