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Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia
Stromal responses elicited by early stage neoplastic lesions can promote tumor growth. However, the molecular mechanisms that underlie the early recruitment of stromal cells to sites of neoplasia remain poorly understood. Here we demonstrate an oncogenic Kras(G12D)-dependent upregulation of GM-CSF i...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3721510/ https://ncbi.nlm.nih.gov/pubmed/22698407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.04.024 |
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