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Oncogenic KRas suppresses inflammation-associated senescence of pancreatic ductal cells
Mutational activation of KRas is the first and most frequently detected genetic lesion in pancreatic ductal adenocarcinoma (PDAC). However, the precise role of oncogenic KRas in the pathogenesis of PDAC is not fully understood. Here, we report that the endogenous expression of oncogenic KRas suppres...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3397918/ https://ncbi.nlm.nih.gov/pubmed/21075310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2010.10.020 |
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