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Oncogenic KRas suppresses inflammation-associated senescence of pancreatic ductal cells

Mutational activation of KRas is the first and most frequently detected genetic lesion in pancreatic ductal adenocarcinoma (PDAC). However, the precise role of oncogenic KRas in the pathogenesis of PDAC is not fully understood. Here, we report that the endogenous expression of oncogenic KRas suppres...

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Detalhes bibliográficos
Main Authors: Lee, Kyoung Eun, Bar-Sagi, Dafna
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397918/
https://ncbi.nlm.nih.gov/pubmed/21075310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2010.10.020
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