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Feedback Regulation of Ras Signaling by Rabex-5-mediated Ubiquitination

Ras proteins play a central role in transducing signals that control cell proliferation, differentiation, motility and survival. The location-specific signaling activity of Ras has been previously shown to be regulated by ubiquitination [1]. However, the molecular machinery that controls Ras ubiquit...

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Bibliografiske detaljer
Main Authors: Xu, Lizhong, Lubkov, Veronica, Taylor, Laura J., Bar-Sagi, Dafna
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436604/
https://ncbi.nlm.nih.gov/pubmed/20655225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.06.051
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