Endothelial nitric oxide signaling regulates Notch1 in aortic valve disease

The mature aortic valve is composed of a structured trilaminar extracellular matrix that is interspersed with aortic valve interstitial cells (AVICs) and covered by endothelium. Dysfunction of the valvular endothelium initiates calcification of neighboring AVICs leading to calcific aortic valve dise...

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Autors principals: Bosse, Authors: Kevin, Hans, Chetan P., Zhao, Ning, Koenig, Sara N., Huang, Nianyuan, Guggilam, Anuradha, LaHaye, Stephanie, Tao, Ge, Lucchesi, Pamela A., Lincoln, Joy, Lilly, Brenda, Garg, Vidu
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058883/
https://ncbi.nlm.nih.gov/pubmed/23583836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2013.04.001
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