Endothelial nitric oxide signaling regulates Notch1 in aortic valve disease

The mature aortic valve is composed of a structured trilaminar extracellular matrix that is interspersed with aortic valve interstitial cells (AVICs) and covered by endothelium. Dysfunction of the valvular endothelium initiates calcification of neighboring AVICs leading to calcific aortic valve dise...

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Detalhes bibliográficos
Main Authors: Bosse, Authors: Kevin, Hans, Chetan P., Zhao, Ning, Koenig, Sara N., Huang, Nianyuan, Guggilam, Anuradha, LaHaye, Stephanie, Tao, Ge, Lucchesi, Pamela A., Lincoln, Joy, Lilly, Brenda, Garg, Vidu
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058883/
https://ncbi.nlm.nih.gov/pubmed/23583836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2013.04.001
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