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Evidence of Aortopathy in Mice with Haploinsufficiency of Notch1 in Nos3-Null Background

Thoracic aortic aneurysms (TAA) are a significant cause of morbidity and mortality in humans. While the exact etiology is unknown, genetic factors play an important role. Mutations in NOTCH1 have been linked to bicuspid aortic valve (BAV) and aortopathy in humans. The aim of this study was to determ...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Cardiovasc Dev Dis
मुख्य लेखकों: Koenig, Sara N., Bosse, Kevin M., Nadorlik, Holly A., Lilly, Brenda, Garg, Vidu
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407710/
https://ncbi.nlm.nih.gov/pubmed/25914885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcdd2010017
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