Endothelial Notch1 Is Required for Proper Development of the Semilunar Valves and Cardiac Outflow Tract

BACKGROUND: Congenital heart disease is the most common type of birth defect, affecting ≈2% of the population. Malformations involving the cardiac outflow tract and semilunar valves account for >50% of these cases predominantly because of a bicuspid aortic valve, which has an estimated prevalence...

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Dades bibliogràfiques
Publicat a:J Am Heart Assoc
Autors principals: Koenig, Sara N., Bosse, Kevin, Majumdar, Uddalak, Bonachea, Elizabeth M., Radtke, Freddy, Garg, Vidu
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843530/
https://ncbi.nlm.nih.gov/pubmed/27107132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.003075
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