Contractile and hemodynamic forces coordinate Notch1b-mediated outflow tract valve formation

Biomechanical forces and endothelial-mesenchymal transition (EndoMT) are known to mediate valvulogenesis. However, the relative contributions of myocardial contractile and hemodynamic shear forces remain poorly understood. We integrated 4D light-sheet imaging of transgenic zebrafish models with movi...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:JCI Insight
Hlavní autoři: Hsu, Jeffrey J., Vedula, Vijay, Baek, Kyung In, Chen, Cynthia, Chen, Junjie, Chou, Man In, Lam, Jeffrey, Subhedar, Shivani, Wang, Jennifer, Ding, Yichen, Chang, Chih-Chiang, Lee, Juhyun, Demer, Linda L., Tintut, Yin, Marsden, Alison L., Hsiai, Tzung K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542601/
https://ncbi.nlm.nih.gov/pubmed/30973827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124460
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky