Spatial and temporal variations in hemodynamic forces initiate cardiac trabeculation

Hemodynamic shear force has been implicated as modulating Notch signaling–mediated cardiac trabeculation. Whether the spatiotemporal variations in wall shear stress (WSS) coordinate the initiation of trabeculation to influence ventricular contractile function remains unknown. Using light-sheet fluor...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Lee, Juhyun, Vedula, Vijay, Baek, Kyung In, Chen, Junjie, Hsu, Jeffrey J., Ding, Yichen, Chang, Chih-Chiang, Kang, Hanul, Small, Adam, Fei, Peng, Chuong, Cheng-ming, Li, Rongsong, Demer, Linda, Packard, René R. Sevag, Marsden, Alison L., Hsiai, Tzung K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Technical Advance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124527/
https://ncbi.nlm.nih.gov/pubmed/29997298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.96672
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