4-Dimensional light-sheet microscopy to elucidate shear stress modulation of cardiac trabeculation

Hemodynamic shear forces are intimately linked with cardiac development, during which trabeculae form a network of branching outgrowths from the myocardium. Mutations that alter Notch signaling also result in trabeculation defects. Here, we assessed whether shear stress modulates trabeculation to in...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Lee, Juhyun, Fei, Peng, Packard, René R. Sevag, Kang, Hanul, Xu, Hao, Baek, Kyung In, Jen, Nelson, Chen, Junjie, Yen, Hilary, Kuo, C.-C. Jay, Chi, Neil C., Ho, Chih-Ming, Li, Rongsong, Hsiai, Tzung K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2016
Soggetti:
Technical Advance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855946/
https://ncbi.nlm.nih.gov/pubmed/27018592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI83496
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