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Inhibition of Notch1 Signaling Reduces Abdominal Aortic Aneurysm in Mice by Attenuating Macrophage-Mediated Inflammation
OBJECTIVE: Activation of inflammatory pathways plays a critical role in the development of abdominal aortic aneurysms (AAA). Notch1 signaling is a significant regulator of the inflammatory response; however, its role in AAA is unknown. METHODS AND RESULTS: In an angiotensin II (AngII)-induced mouse...
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| Опубликовано в: : | Arterioscler Thromb Vasc Biol |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4467024/ https://ncbi.nlm.nih.gov/pubmed/23087364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.254219 |
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