Endothelial nitric oxide signaling regulates Notch1 in aortic valve disease

The mature aortic valve is composed of a structured trilaminar extracellular matrix that is interspersed with aortic valve interstitial cells (AVICs) and covered by endothelium. Dysfunction of the valvular endothelium initiates calcification of neighboring AVICs leading to calcific aortic valve dise...

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Bibliografiska uppgifter
Huvudupphovsmän: Bosse, Authors: Kevin, Hans, Chetan P., Zhao, Ning, Koenig, Sara N., Huang, Nianyuan, Guggilam, Anuradha, LaHaye, Stephanie, Tao, Ge, Lucchesi, Pamela A., Lincoln, Joy, Lilly, Brenda, Garg, Vidu
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058883/
https://ncbi.nlm.nih.gov/pubmed/23583836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2013.04.001
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