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Chronic CRF(1) Receptor Blockade Reduces Heroin Intake Escalation and Dependence-Induced Hyperalgesia

Opioids represent effective drugs for the relief of pain, yet chronic opioid use often leads to a state of increased sensitivity to pain that is exacerbated during withdrawal. A sensitization of pain-related negative affect has been hypothesized to closely interact with addiction mechanisms. Neuroad...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Park, Paula E., Schlosburg, Joel E., Vendruscolo, Leandro F., Schulteis, Gery, Edwards, Scott, Koob, George F.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057367/
https://ncbi.nlm.nih.gov/pubmed/24330252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12120
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