Long-Term Antagonism of κ Opioid Receptors Prevents Escalation of and Increased Motivation for Heroin Intake

The abuse of opioid drugs, both illicit and prescription, is a persistent problem in the United States, accounting for >1.2 million users who require treatment each year. Current treatments rely on suppressing immediate withdrawal symptoms and replacing illicit drug use with long-acting opiate dr...

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Detalhes bibliográficos
Principais autores: Schlosburg, Joel E., Whitfield, Timothy W., Park, Paula E., Crawford, Elena F., George, Olivier, Vendruscolo, Leandro F., Koob, George F.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3850049/
https://ncbi.nlm.nih.gov/pubmed/24305833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1979-13.2013
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